Meet the DoctorLongevityArticlesBooks
SCHEDULE AN APPOINTMENT
Social Media
Jacqueline Seymour
Jan 26, 2022

Health Coach Tip - The Benefits of Urolithin A

Urolithin A(UA) is a compound which is naturally produced by bacteria within the gut microbiome, after consuming ellagitannins or ellagic acid – polyphenols which can be found in foods like pomegranate, berries, nuts, teas, and other foods. Urolithin A has recently been in the longevity spotlight, with research showing that it protects against age-related disease and also slows the aging processes. Here are some of the benefits:

UA improves mitochondrial health

As we age, cellular components called mitochondria become less functional, as do our systems for clearing out dysfunctional mitochondria. Mitochondrial health is central to healthy aging. UA induces mitophagy, the cleaning or recycling of dysfunctional mitochondria, which leads to improved mitochondrial health.

UA improves heart health

Research in animals has shown that UA improves heart health in a variety of ways from supporting heart cells and protecting from atherosclerosis to reducing plasma lipid levels.

UA improves brain health

Research shows that UA supports brain health by decreasing brain inflammation, blocking pro-inflammatory factor NF-kB, and inducing mitophagy. UA also may improve facets of neurodegeneration.

UA improves metabolic health

Research in obese animals shows that UA improves metabolic health by reducing total cholesterol, LDL cholesterol, plasma adiponectin, and liver triglyceride accumulation – which when amok contribute to metabolic conditions. UA has also been shown to increase insulin sensitivity.

UA improves muscle health

Research also shows that UA may prevent age-related muscle decline, improve muscle fiber health, and enhance skeletal muscle strength and performance.

UA improves lifespan

In worms, UA extends lifespan by as much as 45%!

Although most of the research regarding UA is preliminary, the compound is very promising – and several human trials are underway. You may reap the advantages of UA by consuming pomegranate, walnuts and pecans. However, most people do not have the necessary bacteria to produce the amounts of UA needed for these benefits. In that case, there are supplements available!

Longevity Reading

Dr. Frank Lipman
Jan 22, 2024

6 Ways Your Biological Age Matters More than the Number of Candles on Your Cake

When we think about age, we should be thinking of it in terms of two numbers: your actual chronological age and what researchers and some forward-thinking clinicians are now calling “biological” age, which captures the differences in how our bodies change over time. The good news? Medical science is in the first stages of being able to measure the biological processes that underlie aging, and clinicians – myself included – who embrace “longevity medicine” and can use that information to tailor therapies and target lifestyle upgrades to slow that process down.

Healthy Aging
Dr. Frank Lipman
Mar 18, 2024

Unlocking Longevity: Delving into the Next 3 Hallmarks of Aging (Part 3)

In this four-part series on what scientists call “the hallmarks of aging,” the specific biochemical processes that are happening in your body every day, every second, which, taken together, take us from our physical peak in our twenties right on through to the end of our lives. The idea, as I explained, is “know your enemy,” as in, if we can identify what’s going on in the body, we can take steps to fight back against it, whether that’s healthy lifestyle choices now or, down the line, with the help of new treatments being studied in the lab today. My advice? Get familiar with the hallmarks – and what to do about them now – so you can get ahead of the aging process.

Healthy Aging
Dr. Frank Lipman
May 27, 2019

10 Ways To Protect Your Brain and Keep Alzheimer’s At Bay

Far too many of us these days have had some experience with friends or loved ones who are dealing with Alzheimer’s and it’s heart-breaking physical, emotional and mental impact. Though many of us witness the disease at arm’s length, it’s hard not to think about the frightening specter of Alzheimer’s possibly affecting our own brains someday.

Healthy Aging
Dr. Frank Lipman
Nov 15, 2021

7 Ways Tracking Your Heart Rate Variability Can Save Your Health

One often overlooked but extremely helpful health marker I encourage everyone to track is their heart rate variability or (HRV). Learning more about your HRV can give you a better picture of your cardiovascular fitness and your over-all resilience, as well as helping to steer you toward more health-supportive daily behaviors and lifestyle tweaks. Think of HRV as a sort of on-demand monitoring and feedback system for doing stuff that keeps you well.

Dr. Alexandra Davidson
Aug 11, 2023

The Secret to Longevity: The Gut Microbiome

Aging is a natural process, and while we cannot control time, there is a remarkable ecosystem within us—the gut microbiome—that might hold the key to aging gracefully.

Healthy Aging
Dr. Frank Lipman
Oct 19, 2020

4 Ways mTOR Influences How Well You Age

Aging – we’re all doing it, every second of every day. But, how well we do it – ideally with health, vitality and great-looking skin – is another question entirely. The good news is that many studies show that it’s never too late to embrace new habits and start enjoying the health benefits. In other words, it’s still possible to put the brakes on aging!

Healthy Aging
Meet the DoctorLongevityArticlesBooksPodcastsContact Us
© 2023 Dr. Frank Lipman. All rights reserved.
Privacy PolicyTerms of Service